ImaGene-iT scientific publications
Studies in which ImaGene-iT’s contribution has merited co-authorship or acknowledgement.
Over the years, ImaGene-iT’s staff has published numerous scientific papers and review articles.
They cover areas like:
- Animal Biology
- Cancer cell biology and immunotherapy
- Neurobiology – comparative
- Methods
2022
Severe intraventricular hemorrhage causes long-lasting structural damage in a preterm rabbit pup model
Olga Romantsik, Emily Ross-Munro, Susanne Grönlund, Bo Holmqvist, Anders Brinte, Erik Gerdtsson, Suvi Vallius, Matteo Bruschettini, Xiaoyang Wang, Bobbi Fleiss and David Ley
Hydrogels and Cubic Liquid Crystals for Non-Invasive Sampling of Low-Molecular-Weight Biomarkers—An Explorative In Vivo Study
Maxim Morin, Skaidre Jankovskaja, Tautgirdas Ruzgas, Joakim Henricson, Chris D. Anderson, Anders Brinte, Johan Engblom and Sebastian Björklund
2021
Insulin-Like Growth Factor 1 in the Preterm Rabbit Pup: Characterization of Cerebrovascular Maturation following Administration of Recombinant Human Insulin-Like Growth Factor 1/Insulin-Like Growth Factor 1-Binding Protein 3
Magnus Gram, Claes Ekström, Bo Holmqvist, Galen Carey, Xiaoyang Wang Suvi Vallius, William Hellström, Niklas Ortenlöf, Alex Adusei Agyemang,
Lois E.H. Smith, Ann Hellström, Alexandra Mangili, Norman Barton, David Ley
Biodistribution of fluorescence-labelled EGF protein from slow release NanoZolid depots in mouse
Stefan Grudén, Charlott Brunmark, Bo Holmqvist, Erwin D. Brenndörfer, Martin Johansson, Jian Liu c, Ying Zhao a,e, Niklas Axén, Moustapha Hassan
Insulin-like growth factor 1 (IGF-1) in the preterm rabbit pup: Characterization of cerebro-vascular maturation following administration of recombinant human IGF-1/IGF binding protein 3.
Ekström et al. Developmental Neuroscience.
Cell-free oxidized hemoglobin drives reactive oxygen species production and pro-inflammation in an immature primary rat mixed glial cell culture
Alex Adusei Agyemang, Suvi Vallius Kvist, Nathan Brinkman, Thomas Gentinetta, Miriam Illa, Niklas Ortenlöf, Bo Holmqvist, David Ley & Magnus Gram
2020
Insulin-like growth factor 1 (IGF-1) in the preterm rabbit pup: Characterization of cerebro-vascular maturation following administration of recombinant human IGF-1/IGF binding protein 3 (BP-3).
Claes Ekström, Bo Holmqvist, Galen Carey, Xiaoyang Wang, Suvi Vallius Kvist, William Hellström, Niklas Ortenlöf, Alex Adusei Agyemang, Lois E. H. Smith, Ann Hellström, Alexandra Mangili, Norman Barton, Magnus Gram, David Ley (Submitted)
In vivo tumor targeting of biomolecules formulated in slow release Nanozolid depots
Grudén, C. Brunmark, B. Holmqvist, E.D. Brenndörfer, M. Johansson, J. Liu, Y. Zhao, N. Axén, M. Hassan (Submitted)
Application of Prussian white for visualization of H2O2 penetration through skin: in vitro model of H2O2 sensing.
Skaidre Jankovskaja, Anaïs Labrousse, Léa Prévaud, Bo Holmqvist, Anders Brinte, Johan Engblom, Melinda Rezeli, György Marko-Varga and Tautgirdas Ruzgas.
Cell-free oxidized hemoglobin drives reactive oxygen species production and pro-inflammation in a primary rat mixed glial cell culture.
Alex Adusei Agyemang, Suvi Vallius Kvist, Nathan Brinkman, Thomas Gentinetta, Miriam Illa Armengol, Niklas Ortenlöf, Bo Holmqvist, David Ley, Magnus Gram.
2019
Long-term neurological effects of neonatal caffeine treatment in a rabbit model of preterm birth
Van der Veeken L, Grönlund S, Gerdtsson E, Holmqvist B, Deprest J, Ley D, Bruschettini M
Cerebellar Exposure to Cell-Free Hemoglobin Following Preterm Intraventricular Hemorrhage: Causal in Cerebellar Damage?
Agyemang AA, Sveinsdóttir K, Vallius S, Sveinsdóttir S, Bruschettini M, Romantsik O, Hellström A, Smith LEH, Ohlsson L, Holmqvist B, Gram M, Ley D
The heme and radical scavenger α1-3 microglobulin (A1M) confers early protection of the immature brain following preterm intraventricular hemorrhage
(Journal of Neuroinflammation)
High Presence of Extracellular Hemoglobin in the Periventricular White Matter Following Preterm Intraventricular Hemorrhage
Ley D, Romantsik O, Vallius S, Sveinsdóttir K, Sveinsdóttir S, Agyemang AA, Baumgarten M, Mörgelin M, Lutay N, Bruschettini M, Holmqvist B, Gram M.
Integrin α10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival
Matilda Munksgaard Thorén, Katarzyna Chmielarska Masoumi, Cecilia Krona, Xiaoli Huang, Soumi Kundu, Linnéa Schmidt, Karin Forsberg-Nilsson, Marcus Floyd Keep, Elisabet Englund, Sven Nelander, Bo Holmqvist and Evy Lundgren-Åkerlund
2018
Protection of kidney function with human antioxidation protein α1-microglobulin (A1M) in a mouse 177Lu-DOTATATE radiation therapy model
Kristiansson A, Ahlstedt J, Holmqvist B, Brinte Anders Tran T, Forssell-Aronsson E,
Strand S-E, Gram M, Akerstrom B
(Accepted for publication in Antioxidants & Redox Signaling)
Preterm birth and caffeine exposure – effects on the IGF-1 system and cerebellar maturation in rabbit pups.
Kristbjörg Sveinsdóttir1, Matteo Bruschettini1,2, Suvi Vallius Kvist3, Magnus Gram3, Bo Holmqvist4, David Ley1 (ISBN 978-91-7619-635-9)
Stellate cells and mesenchymal stem cells in benign mammary stroma are associated with risk factors for breast cancer – an observational study
Isfoss BL, Holmqvist B, Sand E, Forsell J, Jernström H, Olsson H.
2017
Agyemang AA, Sveinsdóttir K, Vallius S, Sveinsdóttir S, Bruschettini M, Romantsik O, Hellström A, Smith LEH, Ohlsson L, Holmqvist B, Gram M, Ley D.
Cerebellar Exposure to Cell-Free Hemoglobin Following Preterm Intraventricular Hemorrhage: Causal in Cerebellar Damage?
Jonas Ahlstedt, Thuy A Tran, Filip Strand, Bo Holmqvist, Sven-Erik Strand, Magnus Gram, and Bo Åkerström
Biodistribution and pharmacokinetics of recombinant α1-microglobulin and its potential use in radioprotection of kidneys
Björn Logi Isfoss, Bo Holmqvist, Elin Sand, Johan Forsell, Helena Jernström, Håkan Olsson
Stellate cells and mesenchymal stem cells in benign mammary stroma are associated with risk factors for beast cancer (Submitted) BMC Cancer Research
2016
Ley D, Romantsik O, Vallius S, Sveinsdottir K, Sveinsdottir S, Agyeman A, Baumgarten M, Mörgelin M, Lutay N, Bruschettini, Holmqvist B, Gram M
High Presence of Extracellular Hemoglobin in the Periventricular White Matter Following Preterm Intraventricular Hemorrhage. Front. Physiol. 7:330
Isfoss B, Holmqvist B, Jernström, Alm P, Olsson H
The absence of aldehyde dehydrogenase 1 A1-positive cells in benign mammary stroma is associated with risk factors for breast cancer. Breast Cancer – Targets and Therapy 8: 117-124.
Hurley S, Lutay N, Holmqvist B, Shannon O.
The dynamics of platelet activation during the progression of streptococcal sepsis. (Accepted) PLOS ONE
Thesis: Mediatryck, Lund, ISBN 978-91-7619-256-6.
2015
Jonas Ahlstedt · Thuy A Tran · Filip Strand · Bo Holmqvist · Sven-Erik Strand · Magnus Gram · Bo Åkerström
Biodistribution and pharmacokinetics of recombinant α1-microglobulin and its potential use in radioprotection of kidneys
2014
Manli Na · Dongfeng Chen · Bo Holmqvist · Liang Ran · Jie Jin · Johan Rebetz · Xiaolong Fan
Adenovirus assembly is impaired by BMI1-related histone deacetylase activity.
2013
Björn L Isfoss · Bo Holmqvist · Helena Jernström · Per Alm
Women with familial risk for breast cancer have an increased frequency of aldehyde dehydrogenase expressing cells in breast ductules.
2012
Takashi Yamatodani · Bo Holmqvist · Elisabeth Kjellén · Anders Johnsson · Hiroyuki Mineta · Johan Wennerberg
Using intravital microscopy to observe bevacizumab-mediated anti-angiogenesis in human head and neck squamous cell carcinoma xenografts
Isfoss BL, Holmqvist B, Alm P, Olsson H
Distribution of aldehyde dehydrogenase 1-positive stem cells in benign mammary tissue from women with and without breast cancer.
2011
Isfoss BL, Holmqvist B, Alm P, Olsson H (2011) Distribution of ALDH1 positive stem cells in benign epithelial and stromal mammary tissue from women with and without breast cancer. Histopathology [In press]
Lindgren J, Uvdal P, Engdahl A, Lee AH, Alwmark C, Bergquist K-E, Nilsson E, Ekström P, Rasmussen M, Douglas DA, Polcyn MJ, Jacobs LL (2011) Microspectroscopic Evidence of Cretaceous Bone Proteins. PLoSONE 6(4) e19445
Svensson M, Yadav M, Holmqvist B, Lutay N, Svanborg C, Godaly G (2011) Genetic control of acute pyelonephritis and renal scarring; dysfunctional innate immunity in mCxcr2 heterozygous mice. Kidney Int Aug 3. doi: 10.1038/ki.2011.257. [Epub ahead of print]
Yamatodani T, Holmqvist B, Kjéllen E, Oh P, Johnsson A, Mineta H and WennerbergJ (2011). Bevacizumab (Avastin) effects on xenografted human squamous carcinoma tumors – An intravital microscopical study in a mouse dorsal skinfold model. (Submitted).