ImaGene-iT scientific publications
Studies in which ImaGene-iT’s contribution has merited co-authorship or acknowledgement.
2019
The heme and radical scavenger α1-3 microglobulin (A1M) confers early protection of the immature brain following preterm intraventricular hemorrhage
Olga Romantsik1, Alex Adusei Agyemang1, Snjolaug Sveinsdóttir1, Sigurbjörg Rutardóttir2, Bo Holmqvist3,
7 Magnus Cinthio4, Mattias Mörgelin2, Gulcin Gumus5, Helena Karlsson6, Stefan R. Hansson7, Bo Åkerström2, David Ley1† and Magnus Gram1,2,6*†
(Journal of Neuroinflammation)
Integrin α10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival
Matilda Munksgaard Thorén 1,Katarzyna Chmielarska Masoumi 1,Cecilia Krona 2,Xiaoli Huang 1,Soumi Kundu 2,Linnéa Schmidt 1,Karin Forsberg-Nilsson 2,Marcus Floyd Keep 3,Elisabet Englund 4,Sven Nelander 2,Bo Holmqvist 5 andEvy Lundgren-Åkerlund 1,*
2018
Protection of kidney function with human antioxidation protein α1-microglobulin (A1M) in a mouse 177Lu-DOTATATE radiation therapy model
Kristiansson A, Ahlstedt J, Holmqvist B, Brinte Anders Tran T, Forssell-Aronsson E,
Strand S-E, Gram M, Akerstrom B
(Accepted for publication in Antioxidants & Redox Signaling)
Preterm birth and caffeine exposure – effects on the IGF-1 system and cerebellar maturation in rabbit pups.
Kristbjörg Sveinsdóttir1, Matteo Bruschettini1,2, Suvi Vallius Kvist3, Magnus Gram3, Bo Holmqvist4, David Ley1 (ISBN 978-91-7619-635-9)
Stellate cells and mesenchymal stem cells in benign mammary stroma are associated with risk factors for breast cancer – an observational study.
Isfoss BL, Holmqvist B, Sand E, Forsell J, Jernström H, Olsson H.
2017
Agyemang AA, Sveinsdóttir K, Vallius S, Sveinsdóttir S, Bruschettini M, Romantsik O, Hellström A, Smith LEH, Ohlsson L, Holmqvist B, Gram M, Ley D.
Cerebellar Exposure to Cell-Free Hemoglobin Following Preterm Intraventricular Hemorrhage: Causal in Cerebellar Damage?
Jonas Ahlstedt, Thuy A Tran, Filip Strand, Bo Holmqvist, Sven-Erik Strand, Magnus Gram, and Bo Åkerström
Biodistribution and pharmacokinetics of recombinant α1-microglobulin and its potential use in radioprotection of kidneys
Björn Logi Isfoss, Bo Holmqvist, Elin Sand, Johan Forsell, Helena Jernström, Håkan Olsson
Stellate cells and mesenchymal stem cells in benign mammary stroma are associated with risk factors for beast cancer (Submitted) BMC Cancer Research
2016
Ley D, Romantsik O, Vallius S, Sveinsdottir K, Sveinsdottir S, Agyeman A, Baumgarten M, Mörgelin M, Lutay N, Bruschettini, Holmqvist B, Gram M
High Presence of Extracellular Hemoglobin in the Periventricular White Matter Following Preterm Intraventricular Hemorrhage. Front. Physiol. 7:330
Isfoss B, Holmqvist B, Jernström, Alm P, Olsson H
The absence of aldehyde dehydrogenase 1 A1-positive cells in benign mammary stroma is associated with risk factors for breast cancer. Breast Cancer – Targets and Therapy 8: 117-124.
Hurley S, Lutay N, Holmqvist B, Shannon O.
The dynamics of platelet activation during the progression of streptococcal sepsis. (Accepted) PLOS ONE
Thesis: Mediatryck, Lund, ISBN 978-91-7619-256-6.
2015
Jonas Ahlstedt · Thuy A Tran · Filip Strand · Bo Holmqvist · Sven-Erik Strand · Magnus Gram · Bo Åkerström
Biodistribution and pharmacokinetics of recombinant α1-microglobulin and its potential use in radioprotection of kidneys
2014
Manli Na · Dongfeng Chen · Bo Holmqvist · Liang Ran · Jie Jin · Johan Rebetz · Xiaolong Fan
Adenovirus assembly is impaired by BMI1-related histone deacetylase activity.
2013
Björn L Isfoss · Bo Holmqvist · Helena Jernström · Per Alm
Women with familial risk for breast cancer have an increased frequency of aldehyde dehydrogenase expressing cells in breast ductules.
2012
Takashi Yamatodani · Bo Holmqvist · Elisabeth Kjellén · Anders Johnsson · Hiroyuki Mineta · Johan Wennerberg
Using intravital microscopy to observe bevacizumab-mediated anti-angiogenesis in human head and neck squamous cell carcinoma xenografts
Isfoss BL, Holmqvist B, Alm P, Olsson H
Distribution of aldehyde dehydrogenase 1-positive stem cells in benign mammary tissue from women with and without breast cancer.
2011
Isfoss BL, Holmqvist B, Alm P, Olsson H (2011) Distribution of ALDH1 positive stem cells in benign epithelial and stromal mammary tissue from women with and without breast cancer. Histopathology [In press]
Lindgren J, Uvdal P, Engdahl A, Lee AH, Alwmark C, Bergquist K-E, Nilsson E, Ekström P, Rasmussen M, Douglas DA, Polcyn MJ, Jacobs LL (2011) Microspectroscopic Evidence of Cretaceous Bone Proteins. PLoSONE 6(4) e19445
Svensson M, Yadav M, Holmqvist B, Lutay N, Svanborg C, Godaly G (2011) Genetic control of acute pyelonephritis and renal scarring; dysfunctional innate immunity in mCxcr2 heterozygous mice. Kidney Int Aug 3. doi: 10.1038/ki.2011.257. [Epub ahead of print]
Yamatodani T, Holmqvist B, Kjéllen E, Oh P, Johnsson A, Mineta H and WennerbergJ (2011). Bevacizumab (Avastin) effects on xenografted human squamous carcinoma tumors – An intravital microscopical study in a mouse dorsal skinfold model. (Submitted).
2010
Mossberg A, Hou Y, Svensson M, Holmqvist B, Svanborg C (2010) HAMLET treatment delays bladder cancer. J Urology 183:1590-1597
Persson O, Salford LG, Fransson J, Widegren B, Borrebaeck CAK, Holmqvist B (2010). Distribution, cellular localization and therapeutic potential of the tumor associated antigen Ku70/80 in glioblastoma multiforme. J Neurooncology 97:207-215
2009
Nielsen HM, Veerhuis R, Holmqvist B, Janciauskiene S (2009) Binding and uptake of A beta1-42 by primary human astrocytes in vitro. Glia 57:978-88
Odenlund M, Holmqvist B, Baldetorp B, Hellstrand P, Nilsson B-O (2009) Polyamine synthesis inhibition induces S phase cell cycle arrest in vascular smooth muscle cells. Amino Acids 36:273-82
Rebetz J, Na M, Su C, Johansson C, Holmqvist B, Widegren B, Salford L, Arnberg N, Qian Q, Fan X (2009) Adenovirus spread is restricted by receptor masking via excessive fiber expression and early secretion PloSOne, 4(12):e8484
2008
Ekström U, Wallin H, Lorenzo J, Holmqvist B, Abrahamsson M, Aviles FX (2008). Internalization of cystatin C in human cancer cell lines. FEBS 275:4571-4582
Ny L, Li Hua, Mukherjee S, Persson K, Holmqvist B, Zhao D, Shtutin V, Huang H, Weiss LM, Lisanti MP, Factor SM, Chan J, Tanowitz HB, Jelicks LA (2008) A magnetic resonance imaging study of intestinal dilation in Trypanosoma cruzi-infected mice deficient in synthase isoform. Am J Trop Med Hyg 79:760-767.
Plieva FM, Ekström P, Galaev YI, Mattiasson B (2008) Monolithic cryogels with open porous structure and unique double-continuous macroporous networks. Soft Matter 4:2418-2428
2007
Feridani IA, Holmqvist B, H-O Sjogren, Strand S-E, Tennvall J, Baldetorp B (2007) Combined Flow Cytometry and Confocal Laser Scanning Microscopy for evaluation of BR96 antibody cancer cell targeting and internalization. J Cytometry A71A:361-370
2005
Holmqvist B, Falk Olsson C, Svensson Maj-Lis, Svanborg C, Forsell J, Alm P (2005) Expression of nitric oxide synthase isoforms in the mouse kidney; cellular localization and influence by lipopolysaccaride and Toll-like receptor 4. J. Molecular Histology, 36:499-516
Svensson M, Irjala H, Alm P, Holmqvist B, Lundstedt A-C, Svanborg C (2005) Natural history of renal scarring in susceptible mIL-8Rh knock-out mice. Kidney Int 67:103-110
Acknowledged contributions to scientific publications
2011
Hansen C, Angot E, Bergström A-L, Steiner JA, Pieri L, Paul G, Outeiro TF, Melki R, Kallunki P, Fog K, Li J-Y, Brundin P (2011) α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells. J Clin Invest 121:715-725
Saavedra L, Balbi V, Lerche J, Mikami K, Heilmann I, Sommarin M (2011) PIPKs are essential for rhizoid elongation and caulonemal cell development in the moss Physcomitrella patens. Plant J 67:635-647