Pineal organ and melatonin
Pineal organ (epiphysis cerebri), melatonin, and biological rhythms
2000-2011
Ekström P, Meissl H (2003) Evolution of photosensory pineal organs in new light: the fate of neuroendocrine photoreceptors. Phil Trans R Soc Lond B 358:1679-1700
Ekström P, Meissl H (2010) Pineal photoreception and temporal physiology in fish. In Biological clock in fish. Kulczykowska E, Popek W, Kapoor BG (eds.), Science Publishers, Enfield (USA), pp. 35-70.
Forsell J, Ekström P, Novales Flamarique I, Holmqvist B (2001) Expression of pineal UV- and green-like opsins in the pineal organ and retina of teleosts. J Exp Biol 204:2517-2525
Forsell J, Ekström P, Holmqvist B (2002) Molecular identification and developmental expression of UV and green opsin mRNAs in the pineal organ of the Atlantic halibut. Dev Brain Res 136:51-62
1990-1999
Ekström P, Meissl H (1990) Electron microscopic analysis of S-antigen- and serotonin-immunoreactive neural and sensory elements in the photosensory pineal organ of the salmon. J Comp Neurol 292:73-82
Ekström P, Meissl H (1990) Neural elements in the pineal complex of the frog, Rana esculenta. I. Centrally projecting neurons. Visual Neuroscience 4:389-397
Ekström P, Meissl H (1997) The pineal organ of teleosts. Rev Fish Biol Fisheries 7:199-284
Ekström P, Vanecek J (1992) Localization of 2-[125I]-melatonin binding sites in the brain of the salmon Salmo salar L. Neuroendocrinology 55:529-537
Ekström P, Östholm T, Meissl H, Bruun A, Richards RG, Möhler H (1990) Neural elements in the pineal complex of the frog, Rana esculenta. II. GABA-immunoreactive neurons and FMRFamide-immunoreactive efferent axons. Visual Neuroscience 4:399-412
Forsell J, Holmqvist B, Helvik JV, Ekström P (1997) Role of the pineal organ in the photoregulated hatching of the Atlantic halibut. Int J Devl Biol 41:591-595
Meissl H, Ekström P (1991) Action of g-aminobutyric acid (GABA) in the isolated photosensory pineal organ. Brain Res 562:71-78
Meissl H, Ekström P (1993) Extraretinal photoreception by pineal systems: a tool for photoperiodic time measurements. In Trends in Comparative Biochemistry & Physiology 1:1223-1240
Meissl H, Yáñez J, Ekström P, Grossmann E (1994) Benzodiazepines influence melatonin secretion of the pineal organ of the trout in vitro. J Pineal Res 17:69-78
Meissl H, Ekström P (1997) Das Pinealorgan und sein Hormon Melatonin. Spektrum der Wissenschaft (German ed. of Sci Am) Juli 1997:58-64
Meissl H, Ekström P (1991) GABAergic modulation of the neural activity of ganglion cells in the photosensory pineal organ of the trout. Adv Pineal Res 5:141-143
Meissl H, Martin C, Ekström P (1991) Photoreceptive function of the pineal organ: an intrapineal role of melatonin and GABA? Adv Pineal Res 5: 107-113
Meissl H, Anzelius M, Östholm T, Ekström P (1993) Interactions of GABA, benzodiazepines and melatonin in the photosensory pineal organ of salmonid fish. In Melatonin and the pineal gland – From basic science to clinical application. Touitou Y, Arendt J, Pévet P (eds.), Excerpta Medica, Elsevier, Amsterdam, pp. 95-98
Meissl H, Ekström P, Yáñez J, Grossmann (1994) Effects of benzodiazepines on melatonin secretion in the photosensory pineal organ of the teleost, Oncorhynchus mykiss. In Integrative and cellular aspects of autonomic functions: temperature and osmoregulation. Pleschka K, Gerstberger R (eds.), John Libbey Eurotext, Paris, pp 361-369
Östholm T, Ekström P, Ebbesson SOE (1992) Postsmolt change in numbers of acetylcholinesterase-positive cells in the pineal organ of the Pacific coho salmon. Cell Tissue Res 270:281-286
1980-1989
Borg B, Ekström P (1981) Gonadal effects of melatonin in the three-spined stickleback, Gasterosteus aculeatus L., during different seasons and photoperiods. Reprod Nutr Dévelop 21:919-925.
Borg B, Ekström P, van Veen Th (1983) The parapineal organ of teleosts. Acta Zool (Stockh.) 64:211-218
Ekström P (1984) Central neural connections of the pineal organ and retina in the teleost Gasterosteus aculeatus L. J Comp Neurol 226:321-335
Ekström P (1987) Photoreceptors and CSF-contacting neurons in the pineal organ of a teleost fish have direct axonal connections with the brain: an HRP-electron microscopic study. J Neurosci 7:987-995
Ekström P, Korf H-W (1985) Pineal neurons projecting to the brain of the rainbow trout, Salmo gairdneri Richardson (Teleostei). In vitro retrograde filling with horseradish peroxidase. Cell Tissue Res 240:693-700
Ekström P, Korf H-W (1986) Putative cholinergic elements in the photosensory pineal organ and retina of a teleost, Phoxinus phoxinus L. (Cyprinidae). Distribution of choline acetyltransferase immunoreactivity, acetylcholinesterase-positive elements, and pinealofugally projecting neurons. Cell Tissue Res 246:321-329
Ekström P, Korf H-W (1986) Substance P-like immunoreactive neurons in the photosensory pineal organ of the rainbow trout, Salmo gairdneri Richardson (Teleostei). Cell Tissue Res 246:359-364
Ekström P, Meissl H (1988) Intracellular staining of physiologically identified photoreceptor cells and hyperpolarizing interneurons in the teleost pineal organ. Neuroscience 25:1061-1070
Ekström P, Meissl H (1989) Signal processing in a simple vertebrate photoreceptor system: the teleost pineal organ. Physiologia Bohemoslovacica 38:311-326
Ekström P, van Veen Th (1983) Central connections of the pineal organ in the three-spined stickleback, Gasterosteus aculeatus L. (Teleostei). Cell Tissue Res 232:141-155
Ekström P, van Veen Th (1984) Pineal neural connections with the brain in two teleosts, the crucian carp and the European eel. J Pineal Res 1:245-261
Ekström P, Borg B, van Veen Th (1983) Ontogenetic development of the pineal organ, parapineal organ, and retina in the three-spined stickleback, Gasterosteus aculeatus L. (Teleostei). I. Photoreceptor development. Cell Tissue Res 233:593-609
Ekström P, Foster RG, Korf H-W, Schalken JJ (1987) Antibodies against retinal photoreceptor-specific proteins reveal axonal projections from the photosensory pineal organ in teleosts. J Comp Neurol 265:25-33
Ekström P, van Veen Th, Bruun A, Ehinger B (1987) GABA-immunoreactive neurons in the photosensory pineal organ of the rainbow trout form two distinct neuronal populations. Cell Tissue Res 250:87-92
Korf HW, Ekström P (1987) Photoreceptor differentiation and neuronal organization of the pineal organ. In: Fundamentals and clinics in pineal research. Trentini GP , De Gaetani C, Pévet P (eds). Serono Symposia Publications, vol. 44, Raven Press, New York, Raven Press, New York, 35-47.
Korf H-W, Oksche A, Ekström P, van Veen Th, Zigler JS, Gery I, Stein P, Klein DC (1986) S-antigen immunocytochemistry. In: Pineal and Retinal Relationships. D.C. Klein and PJ O’Brien (eds), Academic Press, New York, pp. 343-355
Korf H-W, Foster RG, Ekström P, Schalken JJ (1985) Opsin-like immunoreaction in the retinae and pineal organs of four mammalian species. Cell Tissue Res 242:645-648
Korf H-W, Oksche A, Ekström P, Gery I, Zigler JS, Klein DC (1986) Pinealocyte projections into the mammalian brain revealed with S-antigen antiserum. Science 231:735-737
Meissl H, Ekström P (1986) Antwortmuster pinealer Photorezeptoren der Forelle (Response pattern of pineal photoreceptors of the trout). Verh. Dtsch, Zool. Ges. 79, 227
Meissl H, Ekström P (1987) Adaptation in pineal photoreceptors of the trout. In: Fundamentals and clinics in pineal research. Trentini GP , De Gaetani C, Pévet P (eds). Serono Symposia Publications, vol. 44, Raven Press, New York, 29-33.
Meissl H, Ekström P (1988) Dark and light adaptation of pineal photoreceptors. Vision Research 28:49-56
Meissl H, Ekström P (1988) Photoreceptor responses to light in the isolated pineal organ of the trout, Salmo gairdneri. Neuroscience 25:1071-1076
Östholm T, Ekström P, Bruun A, van Veen Th (1988) Temporal disparity in pineal and retinal ontogeny. Dev Brain Res 42:1-13
van Veen Th, Ekström P, Borg B, Møller M (1980) The pineal complex of the three-spined stickleback, Gasterosteus aculeatus L. A light-, electron microscopical and fluorescence histochemical investigation. Cell Tissue Res 209:11-28
van Veen Th, Ekström P, Nyberg L, Borg B, Vigh-Teichmann I, Vigh B (1984) Serotonin and opsin immunoreactivities in the developing pineal organ of the three-spined stickleback. Cell Tissue Res 237:559-604